| Applications | WB,IHC,IF |
|---|---|
| Species Cross-Reactivity | Human,Mouse,Rat |
| Molecular Weight | 120-135kDa |
| Source | Mouse |
| Isotype | IgG1 |
| Recommended dilutions | WB :1:1000-1:5000 IHC: 1:200-1:500 IF: 1:200-1:500 . Optimal dilutions should be determined by the end user |
| Specificity | Antibody can detects endogenous Human ACE2 protein，predict Cross-Reactivity with Mouse,Rat. |
| Alternative Names | ACE related carboxypeptidase, ACEH, Angiotensin coverting enzyme 2, EC 3.4.17,DKFZP433A014 |
| RRID | AB_3711422 |
| Background | angiotensin I converting enzyme 2(ACE2) Homo sapiens The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. |
| Storage Buffer & Condition | Antigen Affinity Purified IgG in PBS, pH 7.4, containing 0.02% sodium azide as Preservativeand 50% Glycerol. Store at -20°C. Stable for 12 months from date of receipt |
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