| Applications | WB , IHC, IF , IP |
|---|---|
| Species Cross-Reactivity | H,M,R |
| Molecular Weight | 15kDa |
| Isotype | IgG1 |
| Recommended dilutions | WB: 1:1000-1:3000 IHC: 1:200-1:500 IF: 1:200 IP: 1:200 Optimal dilutions should be determined by the end user |
| Specificity | Antibody can detects endogenous Histone H3 (di methyl K27) protein. |
| Alternative Names | H3 histone antibody, HIST1H3A antibody, Histone cluster 1, H3a antibody |
| Background | Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. |
| Storage Buffer & Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Do not aliquot the antibody. |
说明书.pdf
