| Applications | WB,IHC,IF |
|---|---|
| Species Cross-Reactivity | Human,Rat |
| Molecular Weight | ~54kDa |
| Source | Mouse |
| Isotype | IgG1 |
| Recommended dilutions | WB :1:500-1:2000 IHC: 1:100-1:200 IF: 1:50-1:200 Optimal dilutions should be determined by the end user |
| Specificity | Antibody can detects endogenous Phospho ser358 MLKL protein. |
| Alternative Names | Mixed lineage kinase domain like protein, FLJ34389 |
| Gene Id | |
| Swiss Prot No | |
| RRID | AB_3676393 |
| Background | Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358. |
| Storage Buffer & Condition | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol Store at -20°C. Stable for 12 months from date of receipt |
说明书.pdf
